Cytochrome P450 (CYP) monooxygenases and glutathione S-transferases (GST) are enzymes that catalyse chemical modifications of a range of organic compounds.Herbicide resistance has been associated with higher levels of CYP and GST gene expression in some herbicide-resistant weed populations compared to sensitive populations of the same species.By co

Mucopolysaccharidosis type IIIA (MPS IIIA) is an inherited metabolic disorder caused by a lysosomal enzyme deficiency resulting in heparan sulphate (HS) accumulation and manifests with a progressive neurodegenerative phenotype.A naturally occurring MPS IIIA mouse model is invaluable for preclinical evaluation of potential treatments but the ability

Quantifying full left ventricular (LV) metrics including cavity area, myocardium area, cavity dimensions and wall thicknesses from cardiac magnetic resonance (MR) images, and then assessing regional and global cardiac function plays a crucial role in clinical practice.However, due to highly variable cardiac structures across different subjects, it

The paramount discovery of passive accumulation of nanoparticles in tumoral tissues triggered harry potter magsafe case the development of a wide number of different nanoparticles capable of transporting therapeutic agents to tumoral tissues in a controlled and selective way.These nanocarriers have been endowed with important capacities such as sti